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Determine 3 Relative MS responses for 5F-APINACA metabolites. We analyzed metabolites from a two hundred μM 5F-APINACA response as described beneath Procedures and after that utilized values to evaluate relative MS responses for metabolites. Calculation of the metabolite MS responses concerned dividing respective peak parts in the extracted ion chromatograms produced from the total ion scan (Determine A3) from the metabolite concentration as inferred from absorbance. The resulting values for metabolites were then normalized to mother or father drug response as being a measure in their relative variability.

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Most artificial cannabinoids are agonists of the cannabinoid receptors. They are actually intended to be comparable to THC, the organic cannabinoid Using the strongest binding affinity for the CB1 receptor, that is linked to the psychoactive consequences or “large” of cannabis.

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